JMJD1A (Jumonji domain containing 1A), belongs to the JHDM2 histone demethylase family. Histone demethylase specifically demethylates 'Lys-9' of histone H3, thus play a central role in histone code. JMJD1A is involved in spermatogenesis by regulating expression of target genes such as PRM1 and TMP1 that are required for proper packaging and condensation of sperm chromatin.
Applications:
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution:
Western Blot: 1-4ug/ml
Optimal dilutions to be determined by the researcher.
Control Peptide: J7876-41P
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.