Leukemia inhibitory factor (LIF) is a pleiotropic lymphoid factor belonging to the interleukin-6 family of cytokines.
LIF inhibits the differentiation of embryonic stem cells, it is therefore important in ES cell culture.
Human and mouse LIF share 78% amino acid homology, the human version is equally active on human and mouse cells but murine LIF is not active on human cells.
ISOkine™ recombinant human LIF is produced in the endosperm tissue of barley grain (Hordeum vulgare), that exhibits up to 50 times less protease activity than E.coli or mammalian cells.
Barley seed is void of any human or animal viral contaminants that could jeopardize your cell culture.