FcRH1, also known as IRTA5 (Immunoglobulin superfamily Receptor Translocation Associated 5), is a type I transmembrane protein having three extracellular Ig-like domains and cytoplasmic ITAM-like motifs. The FcRH subfamily shares sequence homology with the classical receptors for Ig, and the corresponding genes are localized to human chromosome Iq21-23, a hotspot for translocation events involved in B-cell malignancy. FcRH1 is expressed primarily in B cells.
Applications:
Suitable for use in Flow Cytometry. Other applications not tested.
Recommended Dilution:
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing APC conjugates will result in a substantial loss of activity. APC conjugates are sensitive to light.
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