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Interleukin 13 (IL-13) (FITC)

Cat no: I8435-02F

Supplier: United States Biological
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Interleukin-13 (IL-13) is a multifunctional cytokine whose net principle action is to diminish inflammatory responses. Interleukin (IL)-13 is an important cytokine secreted from type 2 helper T lymphocytes. It is essential for modulating IgE synthesis by human B cells. Previous studies showed that polymorphisms in the IL-13 gene were associated with serum total IgE or allergic asthma. Interleukin (IL)-13 is a pleiotropic cytokine, which shares many biological functions with IL-4. The receptor subunits of IL-13 consist of IL-4Ralpha, IL-13Ralpha1 and IL-13Ralpha2. Applications: Suitable for use in Functional Studies. Other applications have not been tested. Recommended Dilution: Functional Studies: Blocks IL-13 induced proliferation. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.
Catalogue number: I8435-02F
Reactivities: Human
Hosts: Mouse
Size: 100Tests
Form: Supplied as a liquid in 50mM Tris, 100mM Sodium chloride, 1% BSA, 0.02% sodium azide, pH 7.4. Labeled with FITC.
P type: Mab
Isotype: IgG1
Purity: Highly purified (SDS-PAGE).
Additional info: Recognizes human IL-13. Blocks IL-13 induced proliferation.

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