IL-15 is a member of the four alpha-helical bundle family of cytokines with a molecular weight of 14-15kD. Its in vitro activity is very similar to IL-2, except that IL-15 utilizes the IL-15 receptor alpha subunit for binding. IL-15 plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes. It also activates a number of important intracellular signaling molecules. This implies that IL-15 could be essential for the immune responses, allograpt rejection, and the pathogenesis of autoimmune diseases.
Applications:
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution:
Western Blot: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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