Home  >  Products  >  Hypoxanthine Phosphoribosyltransferase 1 (HPRT1, Hypoxanthine-guanine Phosphoribosyltransferase, HGPRTase, HGPRT, HPRT, Lesch-Nyhan Syndrome)
Hypoxanthine Phosphoribosyltransferase 1 (HPRT1, Hypoxanthine-guanine Phosphoribosyltransferase, HGPRTase, HGPRT, HPRT, Lesch-Nyhan Syndrome)

Hypoxanthine Phosphoribosyltransferase 1 (HPRT1, Hypoxanthine-guanine Phosphoribosyltransferase, HGPRTase, HGPRT, HPRT, Lesch-Nyhan Syndrome)

Cat no: H9800-40A

Supplier: United States Biological
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HPRT is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. HPRT, which acts as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP, functions primarily to salvage purines from degraded DNA to renewed purine synthesis. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:5000 Optimal dilutions to be determined by the researcher. Hybridoma: FO myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: H9800-40A
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 50ul
Form: Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
P type: Mab
Isotype: IgG1,k
Purity: Purified by Protein G affinity chromatography.
References: 1. Sculley DG, et al. (1993). Hum. Genet. 90 (3): 195.
Additional info: Recognizes human HPRT.

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