Home  >  Products  >  Hnf4a (Hepatocyte Nuclear Factor 4-alpha, HNF-4-alpha, Nuclear Receptor Subfamily 2 Group A Member 1, Transcription Factor 14, TCF-14, Transcription Factor HNF-4, Hnf-4, Hnf4, Nr2a1, Tcf14)
Hnf4a (Hepatocyte Nuclear Factor 4-alpha, HNF-4-alpha, Nuclear Receptor Subfamily 2 Group A Member 1, Transcription Factor 14, TCF-14, Transcription Factor HNF-4, Hnf-4, Hnf4, Nr2a1, Tcf14)

Hnf4a (Hepatocyte Nuclear Factor 4-alpha, HNF-4-alpha, Nuclear Receptor Subfamily 2 Group A Member 1, Transcription Factor 14, TCF-14, Transcription Factor HNF-4, Hnf-4, Hnf4, Nr2a1, Tcf14)

Cat no: H2006-09

Supplier: United States Biological
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HNF-4 (Hepatocyte nuclear factor 4), a member of the steroid/thyroid nuclear receptor superfamily, is a transcriptional factor which expresses in the liver, intestine, kidney, and pancreatic cells. It contains several functional domains: a ligand-independent activation domain (AF1), a zinc finger DNA binding domain, and a ligand-dependent activation domain (AF2). HNF-4 binds to a specific DNA element as a homodimer and regulates the expression of many genes, involved in glucose, fatty acid, and cholesterol metabolisms. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: H2006-09
Reactivities: Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes rat HNF. Species Crossreactivity: mouse.

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