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Glycogen Synthase Kinase 3 beta (GSK3b) (Agarose)

Glycogen Synthase Kinase 3 beta (GSK3b) (Agarose)

Cat no: G8170-50E

Supplier: United States Biological
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Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3alpha and GSK-3beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility. Applications:
Catalogue number: G8170-50E
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugates: Agarose
Size: 50Tests
Form: Supplied as a liquid in 100mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
P type: Mab
Isotype: IgG2b
Purity: Purified
Additional info: Recognizes human GSK3b.

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