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Products Fas Ligand (FASL) (Biotin)
| Catalogue number: | F0019-66S |
| Reactivities: | Mouse |
| Hosts: | Rat |
| Applications: | Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot |
| Conjugates: | Biotin |
| Size: | 100Tests |
| Form: | Liquid. Purified antibody in PBS containing 0.02% sodium azide. |
| P type: | Mab |
| Isotype: | IgG2a |
| Purity: | (same/more than)95% (by SDS-PAGE). |
| References: | Product Specific Literature References 1. Characterization of the non-functional Fas ligand of gld mice: M. Hahne, et al.; Int. Immunol. 7: 1381 (1995). 2. CD4+ T cells reactivated with superantigen are both more sensitive to FasL-mediated killing and express a higher level of FasL: J.K. Wang, et al.; Cell. Immunol. 179: 153 (1997). 3. Transgenic expression of CD95 ligand on thyroid follicular cells confers immune privilege upon thyroid allografts: L. Tourneur, et al.; J. Immunol. 167: 1338 (2001). GENERAL LITERATURE REFERENCES 1. Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide: H. Russell, et al.; PNAS 90: 4409 (1993), 2. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways: B. Lowin, et al.; Nature 370: 650 (1994). 3. A role for CD95 ligand in preventing graft rejection: D. Bellgrau, et al.; Nature 377: 630 (1995). 4. Fas ligand-induced apoptosis as a mechanism of immune privilege: T.S. Griffith, et al.; Science 270: 1189 (1995). 5. Apoptosis by death factor: S. Nagata; Cell 88: 355 (1997). |
| Additional info: | Recognizes mouse FasL. |
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