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Products Fas (CD95, APO-1) (Biotin)
| Catalogue number: | F0019-62D |
| Reactivities: | Human |
| Hosts: | Mouse |
| Applications: | Flow Cytometry, Immunohistochemistry |
| Conjugates: | Biotin |
| Size: | 100Tests |
| Form: | Liquid. Antibody in 1ml 50mM TRIS, pH 7.4, containing 100mM sodium chloride, 1% BSA and 0.02% sodium azide. |
| P type: | Mab |
| Isotype: | IgG1 |
| Purity: | Highly purified (SDS-PAGE). |
| References: | 1. Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells: F. Leithauser, et al.; Lab. Invest. 69, 415 (1993) 2. Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L): D.C. Huang, et al.; PNAS 96, 14871 (1999) 3. Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD): H. Wajant, et al.; J. Biol. Chem. 275, 24357 (2000) |
| Additional info: | Recognizes human Fas. |
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