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FADD (Protein FADD, FAS-associated Death Domain Protein, FAS-associating Death Domain-containing Protein, Growth-inhibiting Gene 3 Protein, Mediator of Receptor Induced Toxicity, MORT1, GIG3)

FADD (Protein FADD, FAS-associated Death Domain Protein, FAS-associating Death Domain-containing Protein, Growth-inhibiting Gene 3 Protein, Mediator of Receptor Induced Toxicity, MORT1, GIG3)

Cat no: F0019-51N

Supplier: United States Biological
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Fas-associating death domain containing protein (FADD), also known as mediator of receptor induced toxicity (MORT1), is a 24kD cytosolic protein. The protein is involved in both Fas and TNF-R induced cell death pathway. FADD specifically binds to Fas, an association mediated by their homologous death domains. Overexpression of FADD induces apoptosis that can be inhibited by CrmA, a poxvirus protein that blocks both Fas- and TNF-induced cell death. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: F0019-51N
Reactivities: Human, Mouse, Canine
Hosts: Mouse
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
P type: Mab
Isotype: IgG1
Purity: Purified by affinity chromatography.
Additional info: Recognizes human FADD at 28kD. Species Crossreactivity: canine and mouse.

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