Home  >  Products  >  Estrogen Inducible Protein pS2 (Breast Cancer Estrogen Inducible Protein, Breast Cancer Estrogen Inducible Sequence, BCEI, D21S21, Gastrointestinal Trefoil Protein pS2, HP1.A, HPS2, pNR-2, pS2, pS2 Protein, Trefoil Factor 1, TFF1)

Estrogen Inducible Protein pS2 (Breast Cancer Estrogen Inducible Protein, Breast Cancer Estrogen Inducible Sequence, BCEI, D21S21, Gastrointestinal Trefoil Protein pS2, HP1.A, HPS2, pNR-2, pS2, pS2 Protein, Trefoil Factor 1, TFF1)

Cat no: E3557-75B


Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
pS2 is a cysteine-rich, 6.5kD protein found in both estrogen-dependent (breast tumors) and estrogen-independent tissues (normal stomach mucosa). About 60% of breast carcinomas are positive for pS2. pS2 is primarilyexpressed in estrogen receptor-positive breast tumors and is reportedly useful in identifying a subset of estrogen-dependent breast tumors which may respond to endocrine therapy. Applications: Suitable for use in Immunohistochemistry (paraffin-embedded sections). Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: Normal stomach or breast carcinoma tissue sections. Cellular Localization: Cytoplasmic Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: E3557-75B
Reactivities: Human
Hosts: Mouse
Applications: Immunohistochemistry
Size: 250ul
Form: 10mM PBS, pH 7.4, 0.2% BSA
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
References: Mori K et al. Complete primary structure of the human estrogen-responsive gene (pS2) product. J Biochem (Tokyo) 107:73-6 (1990). Rio MC et al. Breast cancer-associated pS2 protein: synthesis and secretion by normal stomach mucosa. Science 241:705-8 (1988). Jeltsch JM et al. Structure of the human oestrogen-responsive gene pS2. Nucleic Acids Res 15:1401-14 (1987). Masiakowski P et al. Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line. Nucleic Acids Res 10:7895-903 (1982).
Additional info: Species Crossreactivity: Crossreacts with Human.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*

Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave