Cell-permeable. A naturally occurring anthraquinone that displays a range of biological activities including anti- inflammatory, anti-tumor and neuroprotective effects. Acts as a potent p56lck tyrosine kinase inhibitor (IC50 = 18.5uM).
Molecular Weight:
~270.24
Solubility:
DMSO (50mM) or aqueous alkali
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with DMSO or aqueous alkali. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.