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Dopamine Receptor D2 (DRD2)

Cat no: D9000-06N

Supplier: United States Biological
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D(2) dopamine receptor is one of five (D1 to D5) receptors for dopamine. Its activity is mediated by G proteins which inhibit adenylyl cyclase. It interacts with GPRASP1, neurabin-2, CLIC6, CADPS and CADPS2. It is a transmembrane protein that belongs to the G-protein coupled receptor 1 family. The unprocessed precursor has a length of 443 amino acids and an estimated molecular mass of 50.6kDa. Genetic variations in DRD2 may determine the genetic susceptibility to alcoholism. A missense mutation in this gene causes myoclonus dystonia and several other defects in this gene are thought to be involved in psychiatric disorders, especially in schizophrenia. Applications: Suitable for use in Direct ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: D9000-06N
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 50ug
Form: Supplied as a lyophilized powder from PBS, pH7.2. Reconstitute with 50ul sterile ddH2O.
P type: Mab
Isotype: IgG
Purity: Purified by Protein G affinity chromatography
Alternative names: Dopamine D2 receptor, GENE NAME: DRD2
Additional info: Recognizes human Dopamine Receptor D2.

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