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Products DNA/RNA Damage Monoclonal Antibody (Clone 15A3)
| Catalogue number: | 10011446 |
| Hosts: | Mouse |
| Applications: | ELISA, Immunohistochemistry |
| Weight: | 0 |
| Form: | 100 microg |
| Antigen: | 8-hydroxy-guanosine-BSA and casein conjugates |
| P type: | Antibodies |
| Isotype: | IgG2b |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | DNA and RNA damage is due to enviromental factors and normal metabolic processes inside the cell, that then hinder the ability of the cell to carry out its functions. Four main types of DNA are endogenous cellular processes oxidation, alkylation, hydrolysis, and of the mismatch bases. Oxidation of bases is caused by reaction with reactive oxygen and nitrogen species (RONS), which include nitric oxide, superoxide, hydroxyl radical, hydrogen peroxide, and peroxynitrite. Numerous studies have shown that RONS causes a variety biomolecular modifications including DNA damage. 8-hydroxy guanine, 8-hydroxy-2 |
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