DIO-1 (Death-inducer Obliterator 1, hDido1, Death-associated Transcription Factor 1, DATF-1, DIDO1, C20orf158, DATF1, KIAA0333)

Cat no: 024586-02

Supplier: United States Biological

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Apoptosis plays an important role in many cellular processes. Dio-1 (Death Inducer- Obliterator-1), a putative transcription factor, has been indicated to function in the onset of apoptosis. Dio-1 expression is upregulated when an apoptosis is detected. It translocates to the nucleus, and activates apoptosis during limb development. Dio-1 expression can be suppressed by caspase inhibitors and Bcl-2 expression. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	024586-02
Reactivities:	Human, Mouse
Hosts:	Rabbit
Applications:	Western Blot
Size:	100ug
Form:	Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
P type:	Pab
Isotype:	IgG
Purity:	Purified by Protein A affinity chromatography.
Additional info:	Recognizes mouse Dio-1 at ~62kD. Species Crossreactivity: human.

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DIO-1 (Death-inducer Obliterator 1, hDido1, Death-associated Transcription Factor 1, DATF-1, DIDO1, C20orf158, DATF1, KIAA0333)

Cat no: 024586-02

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