Dihydrocyclosporin A is a closely related co-metabolite of cyclosporin A. Dihyrocyclosporin A possesses no immuno- suppressant activity and has found use as a control to determine the role of immunosuppression in the pharmacology of cyclosporin A, particularly in the treatment of parasitic infections.
Source:
Dihydrocyclosporin A from Trichoderma sp.
Molecular Weight:
~1204.6
Solubility:
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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