Home  >  Products  >  CTNNB1, Phosphorylated (Ser45) (Catenin beta-1, Beta-catenin, CTNNB, OK/SW-cl.35, PRO2286)

CTNNB1, Phosphorylated (Ser45) (Catenin beta-1, Beta-catenin, CTNNB, OK/SW-cl.35, PRO2286)

Cat no: C2096-64F


Supplier: United States Biological
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Catenin is one of the key downstream effectors in the Wnt signaling pathway. It has been implicated to play an important role in early embryonic development and tumorigenesis. b-catenin can be destabilized by GSK-3b or other kinases by phosphorylating it at serines 33, 37, 45 and threonine 41. Mutations of these phosphorylation sites in b-catenin have been found in many tumor cell lines. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2096-64F
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 1% BSA, 0.02% thimerosal, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human Phospho-b-Catenin at ~90kD. Species Crossreactivity: Mouse and rat.

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