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CTBP1 (C-terminal-binding Protein 1, CtBP1, CTBP)

CTBP1 (C-terminal-binding Protein 1, CtBP1, CTBP)

Cat no: C7947-01J

Supplier: United States Biological
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The C-terminal-binding protein (CtBP) was originally identified as a cellular protein that interacts with a C-terminal motif of adenovirus E1A oncoproteins. CtBP is highly conserved in higher eukaryotes. Vertebrates contain two highly homologous CtBP proteins (CtBP1 and CtBP2) while invertebrates contain a single CtBP. CtBP family proteins share significant sequence homology with D-2-hydroxy acid dehydrogenases. Also, CtBP proteins associate with various proteins and functions as a co-repressor of transcription. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500 Optimal dilutions to be determined by the researcher. Hybridoma: FO myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C7947-01J
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 50ul
Form: Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
P type: Mab
Isotype: IgG2b,k
Purity: Purified by Protein G affinity chromatography.
References: 1. Katsanis N, et al. (1998). Genomics 47 (2): 294-9. 2. Paliwal S, et al. (March 2006). Mol. Cell. Biol. 26 (6): 2360-72. 3. Chinnadurai G (2002). Mol. Cell 9 (2): 213-24.
Additional info: Recognizes human CTBP1.

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