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Complement Component C5a R (CD88, C5a Receptor 1, C5aR1, Complement Component 5a Receptor 1) (APC)

Complement Component C5a R (CD88, C5a Receptor 1, C5aR1, Complement Component 5a Receptor 1) (APC)

Cat no: C0012-01G

Supplier: United States Biological
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C5a R, also known as C5a ligand and CD88, is a 7TM protein expressed on myeloid, endothelial, epithelial, and smooth muscle cells. C5a R binds the activated complement anaphylatoxin C5a. In established allergic environments, this triggers neutrophil and eosinophil chemotaxis and the release of pro-inflammatory mediators. In contrast, C5a R/C5a interactions are protective during allergen sensitization. Human C5a R shares 66% amino acid sequence identity with mouse and rat C5a R. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing APC conjugates will result in a substantial loss of activity. APC conjugates are sensitive to light.
Catalogue number: C0012-01G
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100Tests
Form: Supplied as a liquid in PBS, 0.5% BSA and 0.1% sodium azide.
P type: Mab
Isotype: IgG2a
Purity: Purified by Protein G affinity chromatography.
Additional info: Recognizes human Complement component 5 receptor 1.

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