Home  >  Products  >  CD80 (T-lymphocyte Activation Antigen CD80, Activation B7-1 Antigen, BB1, CTLA-4 Counter-receptor B7.1, B7, CD28LG, CD28LG1, LAB7) (PE/CY5)

CD80 (T-lymphocyte Activation Antigen CD80, Activation B7-1 Antigen, BB1, CTLA-4 Counter-receptor B7.1, B7, CD28LG, CD28LG1, LAB7) (PE/CY5)

Cat no: C2432-02S


Supplier: United States Biological
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CD80, also known as BB1/B7-1, is a 60kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed on activated B cells, T cells, monocytes and dendritic cells. It is a ligand of the two T cell costimulatory molecules, CD28 and CD152 (CTLA-4). The interaction of CD80 (or CD86) with CD28 provides a costimulatory signal for T cells activated through the CD3/TCR complex.1-7 Applications:
Catalogue number: C2432-02S
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Size: 100Tests
Form: Supplied as a liquid in PBS, 0.1% sodium azide and a stabilizing agent. Conjugated to PE/CY5.
P type: Mab
Isotype: IgG1
Purity: Purified
References: 1. Schlossman, S., L. Bloumsell, W. Gilks, J.M. Harlan, C. Kishimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T.F. Tedder, and R.F. Todd, eds. 1995. Leukocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, Oxford. 2. Lenschow, D.J., T.L. Walunas, and J.A. Bluestone. 1996. Annu. Rev. Immunol. 14:233. 3. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD80 Section, Academic Press, New York, p. 335. 4. Yokochi, T., R.D. Holly, and E.A. Clark. 1982. J. Immunol. 2:823. 5. Linsley, P.S., E.A. Clark, and J.A. Ledbetter. 1990. Proc. Natl. Acad. Sci. USA 87:5031. 6. Koulova, L., E.A. Clark, G. Shu, and B. Dupont. 1992. J. Exp. Med. 173:759. 7. Young, J.W., L. Koulova, S.A. Soergel, E.A. Clark, R.M. Steinman, and B. Dupont. 1992. J. Clin. Invest. 90:229.
Additional info: Recognizes human CD80.

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