Home  >  Products  >  CD80 (T-lymphocyte Activation Antigen CD80, Activation B7-1 Antigen, BB1, CTLA-4 Counter-receptor B7.1, B7, CD28LG, CD28LG1, LAB7) (FITC)

CD80 (T-lymphocyte Activation Antigen CD80, Activation B7-1 Antigen, BB1, CTLA-4 Counter-receptor B7.1, B7, CD28LG, CD28LG1, LAB7) (FITC)

Cat no: C2432-02Q

Supplier: United States Biological
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CD80, also known as BB1/B7-1, is a 60kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed on activated B cells, T cells, monocytes and dendritic cells. It is a ligand of the two T cell costimulatory molecules, CD28 and CD152 (CTLA-4). The interaction of CD80 (or CD86) with CD28 provides a costimulatory signal for T cells activated through the CD3/TCR complex.1-7 Applications: Suitable for use in Flow Cytometry, Immunoprecipitation and Western blot. Other applications not tested. Recommended Dilution: Flow Cytometry: 1ug/10e6 cells Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC comjugates are sensitive to light.
Catalogue number: C2432-02Q
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Size: 100Tests
Form: Supplied as a liquid in PBS, 0.1% sodium azide and a stabilizing agent. Labeled with FITC.
P type: Mab
Isotype: IgG1
Purity: Purified.
References: 1. Schlossman, S.et al.,. Leukocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, Oxford. (1995). 2. Lenschow, D.J., et al., Annu. Rev. Immunol. 14:233.(1996). 3. Barclay, A.N.,et al., The Leukocyte Antigens Facts Book, 2nd Edition, CD80 Section, Academic Press, New York, p. 335.(1997). 4. Yokochi, T., et al.,. J. Immunol. 2:823. (1982). 5. Linsley, P.S.,et al.,. Proc. Natl. Acad. Sci. USA 87:5031. (1990). 6. Koulova, L., et al., J. Exp. Med. 173:759. (1992). 7. Young, J.W.,et al., J. Clin. Invest. 90:229. (1992).
Additional info: Recognizes human CD80.

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