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CD8 (Suppressor/Cytotoxic T cell) (PE)

Cat no: C2259-11M

Supplier: United States Biological
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Human CD8 is a heterodimeric protein consisting of an alpha and beta chain, each about 33kD. CD8 is expressed on most thymocytes and on about one third of peripheral blood T cells. CD8 is a co-receptor involved in antigen recognition and binds to the alpha2 and alpha3 domain of MHC Class I molecules. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only pror to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity.
Catalogue number: C2259-11M
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 120Tests
Form: Supplied as a liquid in 50mM Sodium Phosphate pH 7.5, 500mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.3% BSA, 0.04% NaN3.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein A affinity chromatography.
References: 1. Leukocyte Typing II (E.L. Reinherz, et al, eds.) Springer Verlag, New York, (1986). 2. R. Zamoyska, (1994) Immunity 1: 243-246. Leukocyte Typing V ( S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 3. 353-356. J. Sun, et al, (1995) J Exp Med 182: 1275-1280.
Additional info: Recognizes the CD8 alpha chain of approximately 33kD.

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