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CD62L (LECAM-1, L Selectin, Leukocyte, Endothelial Cell Adhesion Molecule) (PE/CY5)

Cat no: C2415-19C

Supplier: United States Biological
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CD62L, also known as L-selectin and LECAM-1, is a 74-94kD type I glycoprotein expressed on neutrophils, monocytes, T and B cell subsets and NK cells. A soluble form of CD62L is present at high levels in blood. Like other selectins, CD62L mediates the initial attachment and rolling of leukocytes on endothelial surfaces which is the prerequisite for leukocyte extravasation from the blood into tissues. More specifically, CD62L is important for the homing of naive lymphocytes via high endothelial venules to peripheral lymph nodes and Peyer
Catalogue number: C2415-19C
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100Tests
Form: Supplied as a liquid in PBS, 0.1% sodium azide and a stabilizing agent. Conjugated to PE/CY5.
P type: Mab
Isotype: IgG1
Purity: Purified
References: 1. Schlossman, S., L. Bloumsell, W. Gilks, J.M. Harlan, C. Kishimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T.F. Tedder, and R.F. Todd, eds. 1995. Leukocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, Oxford. 2. Gearing, A.J.H., and W. Newman. 1993. Immunol. Today 14:506. 3. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD62L Section, Academic Press, New York, p. 298. 4. Lasky, L.A. 1995. Annu. Rev. Biochem. 64:113. 5. Pilarski, L.M., E.A. Turley, A.R. Shaw, W.M. Gallatin, M.P. Laderoute, R. Gillitzer, I.G. Beckman, and H. Zola. 1991. J. Immunol. 147:136.
Additional info: Recognizes human CD62L/L-selectin.

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