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CD62L (LECAM-1, L-Selectin, Leukocyte, Endothelial Cell Adhesion Molecule) (PE)

Cat no: C2415-15D

Supplier: United States Biological
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Human CD62L is as adhesion molecule found on most leukocytes and plays a primary role in mediating initial leukocyte interaction with activated vascular endothelium (1). Human CD62L has signal transduction functions where engagement leads to increased calcium levels and upregulated expression of certain integrins (2). Functional Application: Antibody blocks CD62L function and induces expression of beta-1 and beta-2 integrins (1). Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only pror to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity.
Catalogue number: C2415-15D
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 120Tests
Form: Supplied as a liquid in PBS, pH 7.2, 15% glycerol, 0.2% BSA, 0.05% sodium azide.
P type: Mab
Isotype: IgG2a,k
Purity: Purified by Protein A affinity chromatography.
References: 1). T.A. Springer, (1995) Annu Rev Physiol 57: 827-872. (2). D.A. Steeber, et al, (1997) J Immunol 159: 952-963. (3). Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 420-424.
Additional info: Recognizes the lectin binding domain of CD62L.

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