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CD55 (DAF, Decay Accelerating Factor) (PE/CY5)

Cat no: C2410-50E


Supplier: United States Biological
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CD55, also known as decay accelerating factor (DAF), is a 64-73kD GPI-anchored single chain glycoprotein that is expressed on all cells in contact with serum, including all hematopoietic cells and the vascular endothelium. A soluble form of CD55 is present in plasma and body fluids. CD55 is a member of the regulator of complement activity (RCA) family of proteins and is thought to play a role in the protection of cells from damage by autologous complement by preventing the amplification steps of the complement cascade. CD55 expression increases upon T cell activation and antibodies to CD55 are mitogenic in the presence of phorbol esters.1-5 Applications:
Catalogue number: C2410-50E
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry
Size: 100Tests
Form: Supplied as a liquid in PBS, 0.1% sodium azide and a stabilizing agent. Conjugated to PE/CY5.
P type: Mab
Isotype: IgG1
Purity: Purified
References: 1. Knapp, W., B. Dorken, W.R. GIlks, E.P. Rieber, R.E. Schmidt, H. Stein, A.E.G.K. Von dem Borne, eds. 1989. Leukocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, Oxford. 2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD55 Section, Academic Press, New York, p. 281. 3. Lublin, D.M., and J.P. Atkinson. 1989. Annu. Rev. Immunol. 7:35. 4. Holmes, C.H., K.L. Simpson, S.D. Wainwright, C.G. Tate, J.M. Houlihan, I.H. Sawyer, I.P. Rogers, F.A. Spring, D.J. Anstee, and M.J. Tanner. 1990. J. Immunol. 144:3099. 5. Liszewski, M.K., T.C. Farries, D.M. Lublin, I.A. Rooney, and J.P. Atkinson. 1996. Adv. Immunol. 61:201.
Additional info: Recognizes human CD55.

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