CD49d (Integrin alpha4, VLA4, LHR, Lymphocyte Homing Receptor) (FITC)

Cat no: C2404-46C

Supplier: United States Biological

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Description
Additional Information

Human CD49d molecules are integrin a4 chains that are expressed as heterodimers with CD29 (b1 integrin) or (b7 integrin) and function as adhesion receptors. CD49d/CD29 is mainly expressed on thymocytes and B cells with increased expression on activated T cells. The ligands for CD49d/CD29 include VCAM-1 and fibronectin. Functional Application: Antibody blocks VLA-4 binding to VCAM-1. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	C2404-46C
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry, Immunohistochemistry
Size:	120Tests
Form:	Supplied as a liquid in PBS, pH 7.2, 5% glycerol, 0.2% BSA, 0.05% sodium azide.
P type:	Mab
Isotype:	IgG1
Purity:	Purified by Protein A affinity chromatography.
References:	Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1617-1618. T. Sato, (1995) J Immunol 155: 2938-2947.
Additional info:	Recognizes the CD49d molecule of about 145kD.

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CD49d (Integrin alpha4, VLA4, LHR, Lymphocyte Homing Receptor) (FITC)

Cat no: C2404-46C

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