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CD45RO (APC)

Cat no: C2400-75H


Supplier: United States Biological
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CD45RO is the 180kD isoform of the CD45 glycoprotein not encoded by exons A, B or C. It is expressed on most thymocytes, activated T cells, memory T cells, granulocytes and monocytes, but only on a portion of resting T cells. Monoclonal antibodies against CD45RA and CD45RO seem to define complementary, predominantly non-overlapping populations of resting, peripheral T cells, demonstrating heterogeneity within the CD4 and CD8 subpopulations. CD45RO is the T cell ligand for CD22.1-4 Applications:
Catalogue number: C2400-75H
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size: 100Tests
Form: Supplied as a liquid in PBS, 0.1% sodium azide and a stabilizing agent. Conjugated to APC.
P type: Mab
Isotype: IgG2a
Purity: Purified
References: 1. McMichael, A.K., P.C.L. Beverly, S. Cobbold, M.J. Crumpton, W. Gilks, F.M. Gotch, N. Hogg, M. Horton, N. Ling, I.C.M. MacLennan, D.Y. Mason, C. Milstein, D. Spiegelhalter, and H. Waldmann, eds. 1987. Leukocyte Typing III: White Cell Differentiation Antigens, Oxford University Press, Oxford. 2. Knapp, W., B. Dorken, W.R. GIlks, E.P. Rieber, R.E. Schmidt, H. Stein, A.E.G.K. Von dem Borne, eds. 1989. Leukocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, Oxford. 3. Smith, S.H., M.H. Brown, D. Rowe, R.E. Callard, and P.C. Beverley. 1986. Immunol. 58:63. 4. Norton, A.J., A.D. Ramsay, S.H. Smith, P.C. Beverley, and P.G. Issacson 1986. J. Clin. Pathol. 39:399.
Additional info: Recognizes human CD45RO.

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