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CD45RB (Leukocyte Common Antigen, LCA, Ly-5 T200) (PE)

Cat no: C2400-47G

Supplier: United States Biological
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CD45RB represents an exon B-dependent isoform of CD45 with variable molecular weights of 190, 205 and 220kD. It is expressed primarily on a subset of T and B lymphocytes, monocytes, macrophages and granulocytes (weak). CD4+CD45RA- memory T cells exhibit a differential expression of CD45RB. Bright CD45RB expression correlates with high proliferation rates and interferon-gamma production when compared with dim CD45RB expression. CD45RB expression may be a mechanism for fine tuning the responsiveness of memory cells in vivo.1-3 Applications:
Catalogue number: C2400-47G
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100Tests
Form: Supplied as a liquid in PBS, 0.1% sodium azide and a stabilizing agent. Conjugated to PE.
P type: Mab
Isotype: IgG1
Purity: Purified
References: 1. Schlossman, S., L. Bloumsell, W. Gilks, J.M. Harlan, C. Kishimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T.F. Tedder, and R.F. Todd, eds. 1995. Leukocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, Oxford. 2. Trowbridge, I.S., and M.L. Thomas. 1994. Annu. Rev. Immunol. 12:85. 3. Serra-Pages, C. et al. 1993. Tissue Antigens 42:441.
Additional info: Recognizes human CD45RB.

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