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CD42b (PE) (Glycoprotein Ib, GPIb)

Cat no: C2395-11G


Supplier: United States Biological
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CD42b, also known as gpIb, is a two-chain membrane glycoprotein that forms a noncovalent complex with gpIX (CD42a) on the surface of platelets and megakaryocytes. Binding of the gpIb/gpIX heterodimer to von Willebrand factor bound to exposed subendothelial surfaces is essential for platelet adhesion at sites of injury.1-6 Applications:
Catalogue number: C2395-11G
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Western Blot
Size: 100Tests
Form: Supplied as a liquid in PBS, 0.1% sodium azide and a stabilizing agent. Conjugated to PE.
P type: Mab
Isotype: IgG1
Purity: Purified
References: 1. Schlossman, S., L. Bloumsell, W. Gilks, J.M. Harlan, C. Kishimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T.F. Tedder, and R.F. Todd, eds. 1995. Leukocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, Oxford. 2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD42a, b Section, Academic Press, New York, p. 235. 3. Thorsen, L.I., G. Gaudernack, N. Hack, J.M. Wilkinson, F. Brosstad, N.O. Solum, and N. Crawford. 1988. Brit. J. Haematol. 68:67. 4. Hornby, E.J., S. Brown, J.M. Wilkinson, C. Mattock, and K.S. Authi. 1991. Brit. J. Haematol. 79:277. 5. Berndt, M.C., X.P. Du, and W.J. Booth. 1987. Biochemistry 27:633. 6. Roth, G.J. 1992. Immunol. Today 13:100.
Additional info: Recognizes human CD42b.

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