CD39 was originally described as a B lymphocyte cell surface marker, but it is also present on the surface of natural killer cells, T cells and some endothelial cells. CD39 hydrolyzes the beta- and gamma-phosphate residues of nucleotides, preferring ATP as the substrate. Through its hydrolysis of extracellular nucleotides, CD39 plays a role in the regulation of purinergic signaling. CD39 is also involved in the processes of thromboregulation and vascular inflammation. The amino acid sequence of human CD39 is 77% and 75% identical to that of mouse and rat.
Suitable for use in Flow Cytometry. Other applications not tested.
Flow Cytometry: 10ul labels 1x10e5 cells or 50ul packed whole blood.
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Stable for at least 12 months at 4 degrees C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.