CD37 is a member of the transmembrane 4 superfamily with 4 possible membrane spanning domains. CD37 is strongly expressed on the surface of human peripheral blood B cells and on B cells from the germinal center in lymph nodes. In the ontogeny of the B cells, CD37 appears at a late stage, but is not expressed on plasma cells. A main feature of CD37 is its high content of carbohydrate antigen 45%). CD37 has a very low but signi?cant reactivity with T cells, granulocytes and monocytes.
Suitable for use in Flow Cytometry. Other applications not tested.
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only pror to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity.