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CD26 (Dipeptidyl Peptidase IV, DPPIV, ADABP, ADCP2, TP103, DPP IV) (Biotin)

Cat no: C2277-07A1


Supplier: United States Biological
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CD26 is also known as dipeptidyl peptidase IV (DPP IV) and adenosine deaminase (ADA)-binding protein. It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells. It is upregulated during T-cell activation. CD26 is also expressed on activated B cells, natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. Antibody does not prevent ADA binding to CD26. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry, and Immunoprecipitation. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry (frozen sections): use PAP, APAAP or three stage immunoperoxidase tequnique on acetone-fixed cryostat sections. Flow Cytometry: 1:20 determined on A704 cells Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: C2277-07A1
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Conjugates: Biotin
Size: 100Tests
Form: Supplied as a liquid in 50mM Tris, pH 7.2, 100mM sodium chloride, 1% BSA, 0.02% sodium azide. Labeled with Biotin.
P type: Mab
Isotype: IgG1
Purity: ~95% Purified (SDS-PAGE)
Additional info: Recognizes human CD26 (DPPIV).

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