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CD22 (PE/CY5)

Cat no: C2272-94H


Supplier: United States Biological
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CD22 is a type I integral membrane protein and a member of the sialoadhesin family of cell surface receptors. While it is expressed in the cytoplasm as early as the pro-B cell stage, it appears on the cell surface only upon the expression of membrane-bound IgD. It is found on only the most mature B cells and is rapidly lost with terminal differentiation. CD22 functions in B cell differentiation and homotypic adhesion.1-5 Applications:
Catalogue number: C2272-94H
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Immunohistochemistry
Size: 100Tests
Form: Supplied as a liquid in PBS, 0.1% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified
References: 1. McMichael, A.K., P.C.L. Beverly, S. Cobbold, M.J. Crumpton, W. Gilks, F.M. Gotch, N. Hogg, M. Horton, N. Ling, I.C.M. MacLennan, D.Y. Mason, C. Milstein, D. Spiegelhalter, and H. Waldmann, eds. 1987. Leukocyte Typing III: White Cell Differentiation Antigens, Oxford University Press, Oxford. 2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD22 Section, Academic Press, New York, p. 186. 3. Schwartz-Albiez, R., B. Dorken, D.A. Monner, and G. Moldenhauer. 1991. Int. Immunol. 3:623. 4. Powell, L.D., and A. Varki. 1995. J. Biol. Chem. 270:14243. 5. O
Additional info: Recognizes human CD22.

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