CD19 (FITC)

Cat no: C2269-83D

Supplier: United States Biological

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Description
Additional Information

CD19 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is expressed at all stages of B cell differentiation except terminally differentiated plasma cells. It is also present on the cell surface of follicular dendritic cells. CD19 associates with CD21, CD81, Leu 13 and/or MHC Class II molecules to form a signal transduction complex on the B cell surface. This signaling complex modulates the activation threshold for the B cell antigen receptor (BCR). Applications: Suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 10ul/10e6 cells Immunohistochemistry: Frozen sections Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.

Catalogue number:	C2269-83D
Reactivities:	Human
Hosts:	Mouse
Applications:	Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Size:	100Tests
Form:	Supplied as a liquid in PBS, 0.1% sodium azide. Conjugated to FITC.
P type:	Mab
Isotype:	IgG1
Purity:	Purified
References:	1. McMichael, A.K., P.C.L. Beverly, S. Cobbold, M.J. Crumpton, W. Gilks, F.M. Gotch, N. Hogg, M. Horton, N. Ling, I.C.M. MacLennan, D.Y. Mason, C. Milstein, D. Spiegelhalter, and H. Waldmann, eds. 1987. Leukocyte Typing III: White Cell Differentiation Antigens, Oxford University Press, Oxford. 2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD19 Section, Academic Press, New York, p. 179. 3. Tedder, T.F., L.J. Zhou, and P. Engel. 1994. Immunol. Today 14:437. 4. Fearon, D.T., and R.H. Carter. 1995. Annu. Rev. Immunol. 13:127. 5. Doody, G.M., P.W. Dempsey, and D.T. Fearson. 1996. Curr. Opin. Immunol. 8:378.
Additional info:	Recognizes human CD19.

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CD19 (FITC)

Cat no: C2269-83D

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