Home  >  Products  >  CD178 (Apoptosis Antigen Ligand, APT1LG1, APTL, CD95 Ligand, CD95L, CD95-L, FAS Antigen Ligand, Fas Ligand, FASL, FASLG, Tumor Necrosis Factor Ligand Superfamily Member 6, TNFSF6) (PE)

CD178 (Apoptosis Antigen Ligand, APT1LG1, APTL, CD95 Ligand, CD95L, CD95-L, FAS Antigen Ligand, Fas Ligand, FASL, FASLG, Tumor Necrosis Factor Ligand Superfamily Member 6, TNFSF6) (PE)

Cat no: C2548-91G


Supplier: United States Biological
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Human FAS ligand (CD95L) is a 40kD type II membrane protein that induces apoptosis in cells expressing FAS (CD95) (1, 2). FAS ligand is one of the major effectors of CD8+CTL and NK activitity. Loss of FAS ligand leads to lymphoproliferative and autoimmune disease. Functional Applications: Antibody blocks FAS ligand activity Applications: Suitable for use in Flow Cytometry, Immunohistochemistry and ELISA. Other applications not tested. Recommended Dilution Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only pror to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity.
Catalogue number: C2548-91G
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Flow Cytometry, Immunohistochemistry
Size: 120Tests
Form: Supplied as a liquid in 50mM Sodium Phosphate pH 7.5, 500mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein A affinity chromatography.
Alternative names: TNF Superfamily Member 6
References: 1.)T. Takahashi, et al, (1994) Intl Immunol 6: 1567-1574. 2.) T. Suda, et al, (1997) J Exp Med 186: 2045-2050.
Additional info: Recognizes membrane bound and soluble human FAS ligand.

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