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CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1, INCAM-110) (FITC)

Cat no: C2446-71H


Supplier: United States Biological
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Human CD106 is an endothelial adhesion molecule that binds to a4b1 & a4b7 integrins(VLA-4) and promotes adhesion of lymphocytes, monocytes, eosinophils and basophils. CD106 is also found on follicular dendritic cells, interdigitating recticulum cells and Kupffer cells. Functional Application: Antibody blocks lymphocyte adhesion to CD106 (1). Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C2446-71H
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 120Tests
Form: Supplied as a liquid in 50mM sodium phosphate pH 7.5, 100mM potassium chloride, 150mM sodium chloride, 5% glycerol, 0.2% BSA, 0.04% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein A affinity chromatography.
References: 1. M.H. Thornhill, D.O. Haskard, (1991) J Immunol 146: 592-598. 2. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1764-1767. 3. M. Nagata, et al, (1995) J Immunol 155: 2194-2202. 4. H.E. Chuluyan, et al, (1995) J Immunol 155: 3135-314.
Additional info: Recognizes the VCAM-1 molecule (CD106) which is involved with leukocyte adhesion.

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