Home  >  Products  >  Catenin, beta-like 1 (Beta Catenin-like 1, Beta Catenin-like Protein 1, 5730471K09Rik, Catenin beta-like 1, CTNNBL1, Chromosome 20 Open Reading Frame 3, C20orf33, dJ633O20.1, FLJ21108, Nuclear-associated Protein, Nuclear Protein NAP, NAP, NYD SP19, NYD-SP

Catenin, beta-like 1 (Beta Catenin-like 1, Beta Catenin-like Protein 1, 5730471K09Rik, Catenin beta-like 1, CTNNBL1, Chromosome 20 Open Reading Frame 3, C20orf33, dJ633O20.1, FLJ21108, Nuclear-associated Protein, Nuclear Protein NAP, NAP, NYD SP19, NYD-SP

Cat no: C2069-52Y


Supplier: United States Biological
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Beta-catenin-like protein 1 (CTNNBL1) is an apoptosis inducing protein with a structural homology to beta- catenin and other armadillo family proteins. CTNNBL1 is highly conservered across various species and it is primarily expressed in the nucleus of various tissues (1). In human, CTNNBL1 shows highest expression in skeletal muscle, placenta, heart, spleen, testis, and thyroid tissues. In CHO cells, transient expression of CTNNBL1 cause it to localized to nucleus and induce apoptosis, with apoptosis inducing activity specific to its carboxy-terminal region (1). CTNNBL1 has been linked to possible role in Wnt/beta-catenin-signaling pathway and might have similar function as a beta catenin. CTNNBL1 may play an important role in the development of human obesity (2). Applications: Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:20 Western Blot: 1:2000-1:5000 Immunoprecipitation: 1:40 Immunohistochemistry: 1:100-1:250 Immunocytochemistry: 1:100-1:250 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Manufactured incorporating RabMAb(R) technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Catalogue number: C2069-52Y
Reactivities: Human
Hosts: Rabbit
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ul
Form: Supplied as a liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
P type: Mab
Isotype: IgG
Purity: Supernatant
References: 1. Jabbour L, et al. Genomics 81(3):292-303, 2003. 2. Liu YJ, et al. Hum Mol Genet 7(12):1803-1813, 2008.
Additional info: Recognizes human Beta-catenin-like protein 1.

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