Caspase-7 (CASP7, CASP-7, Apoptotic Protease Mch-3, CMH-1, ICE-like Apoptotic Protease 3, ICE-LAP3, MCH3)

Cat no: C2087-29E2

Supplier: United States Biological

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Caspase-7 is a 34kD protein consisting of two subunits and a short prodomain. The procaspase-7 can be activated by cleavage by upstream caspases to form active caspase-7 in apoptosis. Once activated, caspase-7 cleaves many of the same substrates as caspase-3, including poly (ADP-ribose) polymerase (PARP) and sterol regulatory element binding proteins (SREBPs). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	C2087-29E2
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Western Blot
Size:	100ug
Form:	Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
P type:	Pab
Isotype:	IgG
Purity:	Purified by affinity chromatography.
Additional info:	Recognizes human Caspase-7 at ~20-25kD and ~35-37kD. Species Crossreactivity: mouse and rat.

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Caspase-7 (CASP7, CASP-7, Apoptotic Protease Mch-3, CMH-1, ICE-like Apoptotic Protease 3, ICE-LAP3, MCH3)

Cat no: C2087-29E2

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