Caspase-5 (CASP-5, ICE(rel)-III, Protease ICH-3, Protease TY, CASP5, ICH3)

Cat no: C2087-24Z

Supplier: United States Biological

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Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-5 is also known as Ich-3 and ICErel-III and can proteolytically processed by granzyme B. Over expression of caspase-5 induces apoptosis in Rat-1 and HeLa cells, which can be inhibited by CrmA and Bcl-2. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	C2087-24Z
Reactivities:	Human, Mouse, Rat, Bovine, Non-Human Primate, Rabbit
Hosts:	Rabbit
Applications:	Western Blot
Size:	100ug
Form:	Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
P type:	Pab
Isotype:	IgG
Purity:	Purified by affinity chromatography.
Additional info:	Recognizes human Capsase-5 at ~20kD and ~32kD. Species Crossreactivity: mouse, rat, rabbit, monkey, hamster and bovine.

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Caspase-5 (CASP-5, ICE(rel)-III, Protease ICH-3, Protease TY, CASP5, ICH3)

Cat no: C2087-24Z

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