Caspase-4 (CASP-4, ICE(rel)-II, Protease ICH-2, Protease TX, CASP4, ICH2)

Cat no: C2087-23Y3

Supplier: United States Biological

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The caspase family of cysteine proteases play a key role in apoptosis. Like other caspases in the family, caspase-4 is also synthesized as inactive pro-enzyme that is processed in cells by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-4 consists of large and small subunits which associate to form an active enzyme. Caspase-4 has been implicated involving in Fas-mediated apoptosis. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	C2087-23Y3
Reactivities:	Human
Hosts:	Mouse
Applications:	Western Blot
Size:	100ug
Form:	Supplied as a liquid in PBS, 0.5% BSA, 1.5mM sodium azide, 30% glycerol.
P type:	Mab
Isotype:	IgG1
Purity:	Purified by affinity chromatography.
Additional info:	Recognizes human Caspase-4 at ~43kD.

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Caspase-4 (CASP-4, ICE(rel)-II, Protease ICH-2, Protease TX, CASP4, ICH2)

Cat no: C2087-23Y3

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