Home  >  Products  >  BMI-1 (Polycomb Complex Protein BMI-1, Polycomb Group RING Finger Protein 4, RING Finger Protein 51, BMI1, PCGF4, RNF51)

BMI-1 (Polycomb Complex Protein BMI-1, Polycomb Group RING Finger Protein 4, RING Finger Protein 51, BMI1, PCGF4, RNF51)

Cat no: B2185-02R


Supplier: United States Biological
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Polycomb group (PcG) genes encode chromatin proteins that are involved in the maintenance of cellular memory through epigenetic chromatin modifications. Bmi-1has been identified among the PcG genes as a potent oncogene that plays an important role in the regulation of cell proliferation by suppressing the p16-dependant pathway. Bmi-1 may be use as a therapeutic target for studying stem cell proliferation and renewal. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: B2185-02R
Reactivities: Human, Mouse, Rat, Bovine, Canine, Feline
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes rat BMI-1 at ~34kD. Species Crossreactivity: bovine, canine, feline, human and mouse.

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