Home  >  Products  >  BCL10 (B-cell CLL, B-cell Lymphoma/Leukemia 10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, CARMEN, c-E10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular-E10, Cellular homolog of vCARMEN, CIPER, CLAP, hCLAP,
BCL10 (B-cell CLL, B-cell Lymphoma/Leukemia 10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, CARMEN, c-E10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular-E10, Cellular homolog of vCARMEN, CIPER, CLAP, hCLAP,

BCL10 (B-cell CLL, B-cell Lymphoma/Leukemia 10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, CARMEN, c-E10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular-E10, Cellular homolog of vCARMEN, CIPER, CLAP, hCLAP,

Cat no: B0807-12L

Supplier: United States Biological
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Bcl-10 was originally identified through its direct involvement in t(1;14)(p22;q32) of mucosa-associated lymphoid tissue (MALT) lymphoma. The Bcl-10 molecule is predominantly located in the cytoplasm but expression has also been reported in the nucleus of some lymphomas. Recent reports suggest that Bcl-10 is essential for nuclear factor (NF)-kappaB activation after lymphocyte receptor antigen stimulation and for the development of mature B-cells. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: Neat 10ul labels 1x10e6 cells in 100ul. Optimal dilutions to be determined by the researcher. Recommended Negative Controls Mouse IgG1 Negative Control:RPE Mouse IgG1 Negative Control:RPE Storage and Stability: Lyophilized powder may be stored at 4 degrees C before opening. DO NOT FREEZE! Reconstitute with ddH2O. Aliquot and store at 4C. Stable at 4 degrees C as an undiluted liquid for 6 months. Dilute only prior to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity.
Catalogue number: B0807-12L
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry
Size: 100Tests
Form: Supplied as a lyophilized powder in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Reconstitute with 1ml sterile ddH2O.
P type: Mab
Isotype: IgG1
Purity: Purified by Protein G affinity chromatography.
References: 1. Ye, H. et al. (2005) MALT lymphoma with t(14;18)(q32;q21)/IGH-MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression. J Pathol. 205:293
Additional info: Recognizes human B-cell lymphoma/leukaemia 10 (Bcl-10).

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