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Bcl 2 Modi?ng Factor, CT, Blocking Peptide (Bmf)

Cat no: B0807-08P

Supplier: United States Biological
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Synthetic peptide (ALNGEENRNGAGPR) corresponding to amino acids 171 to 184 of human Bmf (1). Apoptosis is related to many diseases and development. Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3-only proteins, including Bad, Bid, Bik, Hrk, Bim, Noxa, and PUMA, form a growing subclass of the Bcl-2 family. A novel BH3-only protein was recently identi?ed in human and mouse and designated Bmf (for Bcl-2-modi?ng factor) (1). The BH3 domain in Bmf is required both for binding to Bcl-2 proteins and for triggering apoptosis. In healthy cells, Bmf associates with the dynein light chain 2 (DLC2) component of the myosin V motors and is sequestered by the cell
Catalogue number: B0807-08P
Applications: ELISA, Western Blot
Size: 50ug
Form: Supplied as a lyophilized powder.
Purity: Purified 60-70%
References: 1. Puthalakath H, Villunger A, O

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