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BAY 11-7082 ((E)-3-(4-Methylphenylsulfonyl)-2-propenenenitrile)

Cat no: B0184-01


Supplier: United States Biological
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Potential anti-inflammatory agent. Selectively and irreversibly inhibits NF-kB activation by blocking TNF-a-induced phosphorylation of IkB-a without affecting constitutive IkB-a phosphorylation. Inhibits the TNF-a-induced surface expression of adhesion molecules ICAM-1, VCAM-1, and E-selectin in human endothelial cells with IC50 values of 5-10uM Molecular Weight: ~207.25 Solubility: DMSO or EtOH Storage and Stability: May be stored at 4 degrees C. For long-term storage, aliquot and store at 4 degrees C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: B0184-01
Size: 10mg
Form: Supplied as a white to off-white lyophillized powder. Reconstitute with DMSO or EtOH.
Purity: Highly Purified (~99%)

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