Home  >  Products  >  Bad (Bcl2 Antagonist of Cell Death, Bcl-2 Antagonist of Cell Death Protein, BBC2, Bcl-2-binding Component 6, BBC6, BCL-X/Bcl-2 Binding Protein, BCL-X Binding Protein, Bcl-XL/Bcl-2 Associated Death Promoter, Bcl2 Antagonist of Cell Death, BCL2 Associated A
Bad (Bcl2 Antagonist of Cell Death, Bcl-2 Antagonist of Cell Death Protein, BBC2, Bcl-2-binding Component 6, BBC6, BCL-X/Bcl-2 Binding Protein, BCL-X Binding Protein, Bcl-XL/Bcl-2 Associated Death Promoter, Bcl2 Antagonist of Cell Death, BCL2 Associated A

Bad (Bcl2 Antagonist of Cell Death, Bcl-2 Antagonist of Cell Death Protein, BBC2, Bcl-2-binding Component 6, BBC6, BCL-X/Bcl-2 Binding Protein, BCL-X Binding Protein, Bcl-XL/Bcl-2 Associated Death Promoter, Bcl2 Antagonist of Cell Death, BCL2 Associated A

Cat no: B0003-47B

Supplier: United States Biological
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Apoptosis is a critical aspect of cellular function and is implicated in a broad range of human diseases, from cancer to neurodegenerative and cardiovascular diseases. Intrafamilial Bcl-2 protein contacts are thought to regulate key aspects of apoptosis. The corruption of apoptotic instructions is associated with a large subset of human diseases, ranging from cancer and cardiovascular disease to neurodegenerative diseases, and name just a few. Understanding regulation of apoptosis is necessary to constructing a strategy for pharmaceutical intervention. The BH3 domain of Bcl-2 family members has been identified as key to the Bcl-2 regulatory function, although details are not fully elucidated. Applications: Suitable for use in Flow Cytometry, ELISA, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: B0003-47B
Reactivities: Human, Mouse
Hosts: Mouse
Applications: ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.02% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified by ammonium sulfate precipitation.
Alternative names: mBAD
Additional info: Recognizes mouse mBad. Species Crossreactivity: human.

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