A cell-permeable inhibitor of calpain 1 (Ki =120nM) and calpain 2 (Ki =230nM). Also potently inhibits cathepsin B (Ki =100nM), and cathepsin L (Ki=0.6nM). Shown to induce caspase-dependent apoptosis in human acute lymphoblastic leukemia and non-Hodgkin
Catalogue number:
A0002-90
Size:
5mg
Form:
Supplied as a powder.
Purity:
~95% (HPLC)
References:
1. ZU, D.-M., and Uckun, F. M. Clin. Cancer Res. 6, 2456-2463.