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ABCA2 (ATP Binding Cassette 2) (PE)

Cat no: A0004-02S

Supplier: United States Biological
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ATP binding cassette (ABC) transporters are a large family of conserved proteins that translocate molecules across cellular membranes. ABCA2 is a 250kD member of the ABCA subfamily, which is predominantly expressed in the central nervous system, ovary and macrophages. The ABCA2 molecule shares homology with ABCA1 and ABCA7 and plays an important role in lipid metabolism. ABCA2 has been associated with Alzheimer's disease, and studies suggest that ABCA2 could also be involved in drug transport and resistance of tumors to chemotherapy. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: Neat 10ul labels 1x10e6 cells in 100ul. Optimal dilutions to be determined by the researcher. Recommended Negative Controls RAT IgG2a Negative Control:RPE RAT IgG2a Negative Control:RPE Storage and Stability: Lyophilized powder may be stored at 4 degrees C before opening. DO NOT FREEZE! Reconstitute with ddH2O. Aliquot and store at 4C. Stable at 4 degrees C as an undiluted liquid for 6 months. Dilute only prior to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity.
Catalogue number: A0004-02S
Reactivities: Mouse
Hosts: Rat
Applications: Flow Cytometry
Size: 100Tests
Form: Supplied as a lyophilized powder in PBS, pH 7.2, 1% BSA, 0.09% sodium azide. Reconstitute with 1ml sterile ddH2O.
P type: Mab
Isotype: IgG2a
Purity: Purified by Protein G affinity chromatography.
Additional info: Recognizes murine adenosine triphosphate (ATP) binding cassette transporter 2 (ABCA2).

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