DescriptionNovember 18, NY, USA Creative Diagnostics made a new policy--- accelerate the updating rate but remain good quality in last month. For implementing the policy, the scientists in Creative Diagnostics made the detailed updating plan once the policy was published. They chose some key products which have a promising potential in biotech market. Immunoglobulin antigen become the key products of primary updating list.
Immunoglobulin (Ig) contains immunoglobulin antibody (Ab) activity or the chemical structure and the molecule which is similar to antibody. Immune globulin is composed of two identical light chains and two identical heavy chains connected together by disulfide bonds between four peptide chain structure. Immune globulin is divided into five categories: immunoglobulin A (IgA), immunoglobulin G (IgG), , immunoglobulin D (IgD, immunoglobulin E (IgE) and immunoglobulin M (IgM)) .
The immune system is made up of the immune tissues, organs, immune cells and immunological molecules and other components. Ig is one category of the immunological molecules and Immune cell membrane molecules is involved in immunological molecules.Immune globulin is a concept of chemical structure. Chemical basis of all antibodies are immunoglobulin, but immunoglobulin does not have the antibody activity.
Immunoglobulin antigen can be widely used in not only the research of cells, bacteria and human disease but also the development of more advanced products as raw materials. For example, IgE has a close link with asthma. Asthma belongs to type 1 (rapid) allergic diseases and IgE antibody participates in the type 1 hypersensitivity. So It can be said asthma is an IgE-mediated allergic (allergic) diseases. When allergens (like dust mite containing protein and pollen) enters organism for the first time, allergen acts on lymphocytes B and makes it plasma cells, then it produces IgE.
So sensitization can be regarded as the preparation of allergies in the pathogenesis of asthma, but the material basis of sensitization is IgE.
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